Is brain plasticity and aging shaped by the "use it or lose it" concept?
Image: Paul J. Lucassen, PhD, University of Amsterdam, The Netherlands. Credit: Paul J. Lucassen AMSTERDAM, The Netherlands, 2 December 2025 — In a feature published in Brain Medicine, renowned neuroscientist Dr. Paul Lucassen of the University of Amsterdam reflects on a lifetime of work uncovering how the adult brain can adapt and respond to life’s challenges. As head of the Brain Plasticity group, his studies—ranging from brain cell death and regeneration to mental health and
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