Biochemistry

— Pilot Study Paves the Way for Larger Trials on Brain Health Assessment PHILADELPHIA -- In a preliminary investigation, intermittent calorie restriction improved executive function and memory in older adults without cognitive impairments. This 8-week randomized study involved 40 overweight, cognitively healthy seniors with insulin resistance. Researchers compared two dietary strategies: a 5:2 intermittent fasting approach versus a “healthy living” diet, which followed USDA guidelines on

UC Berkeley Engineers Develop Earbuds that Track Brain Signals Linked to Relaxation and Drowsiness Feeling sleepy during work is a common experience, especially after lunch. However, for individuals in high-risk jobs, like driving or operating heavy machinery, drowsiness can be perilous or even fatal. Drowsy driving alone contributes to hundreds of fatal traffic accidents every year across the U.S., and the National Safety Council has highlighted drowsiness as a critical risk in industries like

The United Nations has announced that it will end the employment of nine employees affiliated with the United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA). This decision comes after an inquiry revealed possible connections between these individuals and Hamas-led attacks on Israel that took place on October 7. The investigation, led by the UN Office of Internal Oversight Services (OIOS), was initiated after accusations surfaced from Israel last year, alleging

— Lack of Institutional Support and Knowledge rank as Key Factors A recent systematic review of 283 studies has determined that a lack of institutional backing remains the top reason clinicians hesitate to intervene in addiction cases, as highlighted by the findings. In their analysis, Wilson Compton, MD, MPE, deputy director of the National Institute on Drug Abuse (NIDA), and his colleagues reported in JAMA Network Open that 81.2% of the reviewed articles cited the institutional environment as

— Potential for durable responses with alternative antigen-targeted therapy A promising new treatment targeting a different antigen has shown success among patients with large B-cell lymphoma who previously relapsed after receiving CD19-directed CAR T-cell therapy (CAR19), according to findings from a phase I dose-finding study. In the study, 38 patients who had not responded to CAR19 achieved a 68% overall response rate and a 53% complete response rate following treatment with autologous