Decline in Suicide Rates Among Cancer Patients; Circadian Rhythm Enhancement; HIV Vaccine as Cancer Therapy?

Decline in Suicide Rates Among Cancer Patients; Circadian Rhythm Enhancement; HIV Vaccine as Cancer Therapy?

— Coverage on Cancer-Related News, Features, and Discussion

Although nationwide suicide rates are steadily increasing, the trend among cancer patients is on the decline, according to a report. (Translational Psychiatry)

An updated guideline from the American Society for Radiation Oncology emphasizes patient-centric care in radiation therapy for patients with bone metastases.

New clinical guidelines now advocate for a personalized strategy when choosing contraceptive methods for women at risk of gynecologic cancers. (International Journal of Gynaecology and Obstetrics)

Restoring a balanced circadian rhythm could potentially enhance the effectiveness of immune checkpoint inhibitors. (Nature Immunology)

AstraZeneca revealed that their antibody-drug conjugate, datopotamab deruxtecan, showed a "clinically meaningful improvement" in overall survival (OS) when compared to chemotherapy for patients with advanced nonsquamous non-small cell lung cancer.

Merck shared that combining neoadjuvant pembrolizumab (Keytruda) with chemotherapy, followed by adjuvant pembrolizumab, led to a significant increase in OS for patients with early-stage, high-risk triple-negative breast cancer.

The FDA has extended its approval of the CAR T-cell therapy lisocabtagene maraleucel (Breyanzi) to include adult patients with relapsed or refractory mantle cell lymphoma.

Ikena Oncology announced cessation of their clinical development program for IK-930, a TEAD1-selective Hippo pathway inhibitor, yet cancer patients who have seen benefits will still be permitted to continue treatment.

Sagent Pharmaceuticals has voluntarily recalled vials of docetaxel injection due to potential contamination with particulate matter, the FDA announced.

The FDA also granted an accelerated approval to selpercatinib (Retevmo), specifically for pediatric patients with RET-altered metastatic thyroid cancer and certain solid tumors.

Is it possible that an HIV vaccine could play a role in preventing cancer? (Science Advances)

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