— Nearly All APOE4 Homozygous Individuals Develop Alzheimer’s Emerging evidence from multiple research cohorts suggests that carrying two copies of the APOE4 gene variant is more than just a risk factor; it may drive a unique genetic form of Alzheimer’s disease. Data on clinical features, biomarkers, and pathology indicate that APOE4 homozygous individuals could have a distinct genetic trajectory in Alzheimer’s onset, according to Juan Fortea, MD, PhD, from the Hospital of Sant Pau in

Researchers from Johns Hopkins Medicine have engineered an artificial lymph node that may offer a promising new way to fight cancer, according to findings demonstrated in both mice and human cells. This synthetic node, designed to function as a teaching hub for the immune system's T-cells, can potentially instruct them to recognize and target cancer cells more effectively, according to the study findings published recently online and in the June 6 edition of *Advanced Materials*. The