The United States, as one of the founding nations of the World Health Organization (WHO), has played a pivotal role in many of the organization’s major public health successes. These include the eradication of smallpox and significant progress in combating polio, HIV, Ebola, influenza, tuberculosis, malaria, neglected tropical diseases, antimicrobial resistance, and food safety challenges. Given this longstanding collaboration, WHO expresses concern over the United States’ formal notice of